Английская Википедия:GABA transaminase inhibitor
Материал из Онлайн справочника
In pharmacology, a GABA transaminase inhibitor is an enzyme inhibitor that acts upon GABA transaminase.[1] Inhibition of GABA transaminase enzymes reduces the degradation of GABA, leading to increased neuronal GABA concentrations.
Examples include valproic acid,[2] vigabatrin,[3][4] phenylethylidenehydrazine (and drugs that metabolize to it, such as phenelzine[5]), ethanolamine-O-sulfate (EOS), and L-cycloserine.[6]
Certain members of this class are used as anticonvulsants.
References
Шаблон:GABA agonists and antagonists Шаблон:Anticonvulsants Шаблон:Enzyme inhibition
