Английская Википедия:GPR143

Материал из Онлайн справочника
Версия от 23:35, 10 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}} {{Infobox protein family | Symbol = Ocular_alb | Name = Ocular albinism type 1 protein | image = | width = | caption = | Pfam = PF02101 | Pfam_clan = CL0192 | InterPro = IPR001414 | SMART = | PROSITE = | MEROPS = | SCOP = | TCDB = | OPM family = | OPM protein = | CAZy = | CDD = }} '''G-p...»)
(разн.) ← Предыдущая версия | Текущая версия (разн.) | Следующая версия → (разн.)
Перейти к навигацииПерейти к поиску

Шаблон:Short description Шаблон:Infobox gene Шаблон:Infobox protein family G-protein coupled receptor 143, also known as Ocular albinism type 1 (OA1) in humans, is a conserved integral membrane protein with seven transmembrane domains and similarities with G protein-coupled receptors (GPCRs) that is expressed in the eye and epidermal melanocytes.[1][2][3] This protein encoded by the GPR143 gene,[4][5] whose variants can lead to Ocular albinism type 1.[6]

The GPR143 gene is regulated by the Microphthalmia-associated transcription factor.[7][8]

L-DOPA is an endogenous ligand for OA1.[9]

Interactions

GPR143 has been shown to interact with GNAI1.[5]

References

Шаблон:Reflist

Further reading

Шаблон:Refbegin

Шаблон:Refend

External links

Шаблон:G protein-coupled receptors Шаблон:Transmembranereceptor-stub