Английская Википедия:GPR182

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Версия от 23:36, 10 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in humans}} {{Infobox_gene}} '''GPR182''' (or '''G protein-coupled receptor 182''') is a human gene (and associated protein) which is an orphan G-protein coupled receptor.<ref name="pmid12679517">{{cite journal |vauthors=Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wr...»)
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Шаблон:Short description Шаблон:Infobox gene GPR182 (or G protein-coupled receptor 182) is a human gene (and associated protein) which is an orphan G-protein coupled receptor.[1]

When this gene was first cloned, it was proposed to encode an adrenomedullin receptor.[2] However, when the corresponding protein was expressed, it was found not to respond to adrenomedullin (ADM).[3]

It was subsequently shown that a different GPCR, CALCRL when complexed with RAMP2 can function as an ADM receptor.[4]

References

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Further reading

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External links

Шаблон:G protein-coupled receptors Шаблон:Transmembranereceptor-stub