Английская Википедия:GPR6
Материал из Онлайн справочника
Шаблон:Short description Шаблон:Infobox gene G protein-coupled receptor 6, also known as GPR6, is a protein which in humans is encoded by the GPR6 gene.[1][2]
Function
GPR6 is a member of the G protein-coupled receptor family of transmembrane receptors. It has been reported that GPR6 is both constitutively active but in addition is further activated by sphingosine-1-phosphate.[3]
GPR6 up-regulates cyclic AMP levels and promotes neurite outgrowth.[4]
Ligand
Inverse Agonist
Evolution
Paralogues to GPR6 gene
Source:[6]
- GPR3
- GPR12
- S1PR5
- S1PR1
- CNR1
- S1PR2
- LPAR2
- CNR2
- MC1R
- S1PR3
- S1PR4
- GPR119
- MC3R
- MC4R
- MC5R
- LPAR1
- LPAR3
- MC2R
See also
References
Further reading
External links
Шаблон:G protein-coupled receptors
Шаблон:Transmembranereceptor-stub