Английская Википедия:GPX5

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Версия от 23:45, 10 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}} '''Glutathione peroxidase 5''' (GPx-5), also known as '''epididymal secretory glutathione peroxidase''' is an enzyme that in humans is encoded by the ''GPX5'' gene.<ref name="entrez">{{cite web | title = Entrez Gene: glutathione peroxidase 5 (epididymal androgen-related protein)| url = https:...»)
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Шаблон:Short description Шаблон:Infobox gene Glutathione peroxidase 5 (GPx-5), also known as epididymal secretory glutathione peroxidase is an enzyme that in humans is encoded by the GPX5 gene.[1][2]

GPx-5 belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[1]

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Further reading

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