Английская Википедия:Gamma-Melanocyte-stimulating hormone
γ-Melanocyte-stimulating hormone (γ-MSH) is an endogenous peptide hormone and neuropeptide.[1] It is a melanocortin, specifically, one of the three types of melanocyte-stimulating hormone (MSH), and is produced from proopiomelanocortin (POMC).[1] It is an agonist of the MC1, MC3, MC4, and MC5 receptors.[1] It exists in three forms, γ1-MSH, γ2-MSH, and γ3-MSH.[2]
γ-MSH regulated cardiovascular functions. γ-MSH effects are measured through the effects it has on the central neural pathway dispersed throughout the kidney.[3] It is not moderated based on tubular sodium transport. Gamma-MSH activates MC3R in renal tubular cells by limiting sodium absorption by inhibiting the central neural pathway.[3] This regulates sodium balance and blood pressure. If MC3R is absent then there is resistance in γ-MSH which results in hypertension on HSD.[4]
See also
References
Шаблон:Hormones Шаблон:Neuropeptides Шаблон:Melanocortin receptor modulators
