Английская Википедия:Glecaprevir
Шаблон:Short description Шаблон:Drugbox
Glecaprevir (INN,[1]) is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that was identified jointly by AbbVie and Enanta Pharmaceuticals. It is being developed as a treatment of chronic hepatitis C infection in co-formulation with an HCV NS5A inhibitor pibrentasvir. Together they demonstrated potent antiviral activity against major HCV genotypes and high barriers to resistance in vitro.[2]
On 19 December 2016, AbbVie submitted a new drug application to the U.S. Food and Drug Administration for the glecaprevir/pibrentasvir (trade name Mavyret) regimen for the treatment of all major genotypes (1–6) of chronic hepatitis C. On 3 August 2017 the FDA approved the combination for hepatitis C treatment.[3] In Europe, it was approved on 17 August 2017 for the same indication, under the trade name Maviret.[4]
See also
References
Шаблон:Antiinfective-drug-stub
- Английская Википедия
- Carboxamides
- Carbamates
- Cyclopropanes
- Drugs developed by AbbVie
- Ethers
- NS3/4A protease inhibitors
- Organofluorides
- Pyrrolidines
- Quinoxalines
- Sulfonamides
- Tert-butyl compounds
- Cyclopentanes
- Страницы, где используется шаблон "Навигационная таблица/Телепорт"
- Страницы с телепортом
- Википедия
- Статья из Википедии
- Статья из Английской Википедии