Английская Википедия:Glycoside hydrolase family 45
In molecular biology, glycoside hydrolase family 45 is a family of glycoside hydrolases.
Glycoside hydrolases Шаблон:EC number are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]
Glycoside hydrolase family 45 CAZY GH_45 comprises enzymes with only one known activity; endoglucanase (Шаблон:EC number). This family is also known as cellulase family K.[8] The best conserved region in these enzymes is located in the N-terminal section. It contains an aspartic acid residue which has been shown[9] to act as a nucleophile in the catalytic mechanism. This also has several cysteines that are involved in forming disulphide bridges.
References
Шаблон:InterPro content Шаблон:Sugar hydrolases Шаблон:Enzymes Шаблон:Portal bar
