Английская Википедия:Glycoside hydrolase family 7
Шаблон:Short description Шаблон:Infobox protein family In molecular biology, glycoside hydrolase family 7 is a family of glycoside hydrolases Шаблон:EC number, which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]
Glycoside hydrolase family 7 CAZY GH_7 comprises enzymes with several known activities including endoglucanase (Шаблон:EC number) and cellobiohydrolase (Шаблон:EC number). These enzymes were formerly known as cellulase family C.
Exoglucanases and cellobiohydrolases[8] play a role in the conversion of cellulose to glucose by cutting the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain. Structurally, cellulases and xylanases frequently consist of a catalytic domain joined to a cellulose-binding domain (CBD) via a linker region that is rich in proline and/or hydroxy-amino acids. In type I exoglucanases, the CBD domain is found at the C-terminal extremity of these enzyme (this short domain forms a hairpin loop structure stabilised by 2 disulphide bridges).
References
Шаблон:InterPro content Шаблон:Sugar hydrolases Шаблон:Enzymes Шаблон:Portal bar
