Английская Википедия:H295R

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Версия от 01:58, 18 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} '''H295R''' (also referred to as NCI-H295R) is an angiotensin-II-responsive steroid-producing adrenocortical cell line.<ref name="TP-150519-001">{{cite journal |vauthors=Wang T, Rainey WE |title= Human Adrenocortical Carcinoma Cell Lines. |journal= Mol. Cell. Endocrinol. |volume= 351 |issue= 1 |pages= 58–65 |year= 2012 |pmid= 21924324 |doi=...»)
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H295R (also referred to as NCI-H295R) is an angiotensin-II-responsive steroid-producing adrenocortical cell line.[1] It was initially isolated in 1980 from a 48-year-old female patient diagnosed with adrenocortical carcinoma.[1][2] The initial polyclonal populations of tumor cells obtained from the patients' tumor were cultured and the resultant cell line was called NCI-H295.[1][2] Because of slow growth rates and easy detachment of the original NCI-H295 strains, efforts were made to select a population of cells with better monolayer attachment and more rapid growth.[1] Three strains were developed, based on the serum supplement used for growth, which have been termed H295R-S1, H295R-S2 and H295R-S3.[1][3] All three strains grow as adherent monolayer cultures.[1]

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