Английская Википедия:HLA-A36

Материал из Онлайн справочника
Версия от 04:38, 18 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Technical|date=May 2017}} {{SerotypeA_normal | locus = A | type = 36 | allelegroup = 36 | oneallele = 01 | alleles = 1 | alias = | nick1 = A36 | allele1 = 01 | dominant = 01 <!-------------comments do not need period--------------------------> | mode = Africa (North and East) and Central Asia | lead_comment = is rare HLA-A allel...»)
(разн.) ← Предыдущая версия | Текущая версия (разн.) | Следующая версия → (разн.)
Перейти к навигацииПерейти к поиску

Шаблон:Technical

Шаблон:SerotypeA normal

Distribution

HLA A36 frequencies
freq
ref. Population (%)
Kenya 6.6
[1] N. African (non-caucasian) 4.5
[2] Mossi (Burkina Faso) 3.8
[3] Beti (Cameroon) 3.7
[1] Mongolian 3.1
Lusaka (Zambia) 3.1
[1] Harare Shona (Zimbabwe) 2.9
[1] Uyghurs (China) 2.6
[3] Bamileke (Cameroon) 2.6
[4] Amman (Jordan) 2.4
[2] Fulani 2.0
[1] Sweden 1.6
Tswana (S. Africa) 1.2
Kampala (Uganda) 1.2
[1] Spain 0.9
Bubi (Equatorial Guinea) 0.5
[1] !Kung (San) 0.0
Berber (Morocco) 0.0

A36 is largely limited to Africa. Outside Africa, more than half of the populations have no A36 and the majority that do, have only trace levels. The exception is in Central/East Central Asia. This appears not to be coincidental. HLA DR3-DQ2 linkage and frequency indicates a strong possibility of a recent migration from either North or West Africa in which the DR3-DQ2 (notably DRB1*0302) and A*33-B*58 haplotypes were carried into and redistributed from Central Asia into the surrounding populations.

References

Шаблон:Reflist

Шаблон:HLA-A serotypes