Английская Википедия:Huprine X
Шаблон:Short description Шаблон:Drugbox
Huprine X is a synthetic cholinergic compound developed as a hybrid between the natural product Huperzine A and the synthetic drug tacrine. It is one of the most potent reversible inhibitors of acetylcholinesterase known, with a binding affinity of 0.026nM,[1] as well as showing direct agonist activity at both nicotinic and muscarinic acetylcholine receptors.[2][3] In animal studies it has nootropic and neuroprotective effects, and is used in research into Alzheimer's disease,[4][5][6][7] and although huprine X itself has not been researched for medical use in humans, a large family of related derivatives have been developed.[8][9][10]
References
Шаблон:Acetylcholine metabolism and transport modulators
