Английская Википедия:Hydramethylnon
Шаблон:Chembox Hydramethylnon is an organofluorine compound. It is also known as AC 217,300. It is in a chemical class called trifluoromethyl aminohydrazone, which is a metabolic inhibitor. It is classified as a pesticide designed to control insects that are harmful to humans.[1] It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation. It is used primarily as an insecticide in the form of baits for cockroaches and ants.[2] Some brands of insecticides that include hydramethylnon are Amdro, Blatex, Combat, Cyaforce, Cyclon, Faslane, Grant's, Impact, Matox, Maxforce, Pyramdron, Siege, Scuttle and Wipeout. Hydramethylnon is a slow-acting poison with delayed toxicity that needs to be eaten to be effective.[3]
Toxicology
Hydramethylnon has low toxicity in mammals.[2][3] The oral Шаблон:LD50 is 1100–1300 mg/kg in rats and above 28,000 mg/kg in dogs.[3] Hydramethylnon is toxic to fish; the 96-hour LC50 in rainbow trout is 0.16 mg/L, 0.10 mg/L in channel catfish, and 1.70 mg/L in bluegill sunfish.
Hydramethylnon, when fed to rats for two years, led to an increase in uterine and adrenal tumors at the highest dose; therefore, the Environmental Protection Agency classifies hydramethylnon as a possible human carcinogen.[3]
See also
- Fipronil, another insecticide used for similar purposes
References
External links
- Шаблон:PPDB
- Hydramethylnon Technical Fact Sheet - National Pesticide Information Center
- Hydramethylnon General Fact Sheet - National Pesticide Information Center
- Hydramethylnon Pesticide Information Profile - Extension Toxicology Network
- Maxforce MSDS.
- Amdro MSDS
