Английская Википедия:Hydrochlorothiazide/triamterene

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Hydrochlorothiazide/triamterene, also known as co-triamterzide, is a fixed-dose combination medication of hydrochlorothiazide and triamterene.[1][2][3] It is used to treat high blood pressure and edema (swelling).[1][2][3] Specifically it is used in those who develop low blood potassium (hypokalemia) when on only hydrochlorothiazide.[1][2] It is taken by mouth.[1][2][3]

Side effects may include nausea, trouble sleeping, dizziness, feeling light headed with standing, kidney problems, allergies, and muscle cramps.[1][2] Other serious side effects may include high blood potassium.[1][2] Use in pregnancy and breastfeeding is not generally recommended.[1][2] Use in those with significant kidney problems is not recommended.[1][2] It decreases blood pressure mainly by hydrochlorothiazide while triamterene decreases the amount of potassium lost.[1][2]

The combination was approved for medical use in the United States in 1965.[4] In 2021, it was the 112th most commonly prescribed medication in the United States, with more than 5Шаблон:Nbspmillion prescriptions.[5][6]

References

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Шаблон:Diuretics Шаблон:GlaxoSmithKline Шаблон:Portal bar