Английская Википедия:Indium (111In) capromab pendetide
Indium (111In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer.[1] Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA.[2] Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single-photon emission computed tomography (SPECT).[1]
Early trials with yttrium (90Y) capromab pendetide were also conducted.[3]
References
Шаблон:Radiopharmaceuticals Шаблон:Monoclonals for tumors
Шаблон:Monoclonal-antibody-stub
Шаблон:Antineoplastic-drug-stub
Шаблон:Nuclear-med-stub