Английская Википедия:Isoniazid/pyridoxine/sulfamethoxazole/trimethoprim
Шаблон:Short description Шаблон:Infobox drug
Isoniazid/pyridoxine/sulfamethoxazole/trimethoprim (INH/B6/CTX) is a fixed-dose combination medication for the prevention of opportunistic infections in HIV/AIDS.[1] It combines isoniazid, pyridoxine, sulfamethoxazole, and trimethoprim.[1] Specifically it is used to prevent tuberculosis, toxoplasmosis, pneumonia, malaria, and isosporiasis.[2] It is taken by mouth.[1]
Side effects may include trouble concentrating, numbness, vomiting, and rash.[2] Serious side effects may include liver problems.[2] Caution may be required in people with G6PD deficiency.[2] While it has not been well studied, use in pregnancy appears to be okay.[2]
It is on the World Health Organization's List of Essential Medicines.[1] While benefits include being able to take less pills, it is unclear if this version changes peoples adherence to treatment.[2] Other studies, however, have found fixed-dose combinations to be useful for this purpose.[2]
References
Шаблон:Antimycobacterials Шаблон:Portal bar Шаблон:Antiinfective-drug-stub