Английская Википедия:ICA1

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Шаблон:Short description Шаблон:Cs1 config Шаблон:Infobox gene Islet cell autoantigen 1 is a protein that in humans is encoded by the ICA1 gene.[1][2][3]

This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjögren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.[3]

References

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Further reading

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