Английская Википедия:Isoquercetin

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Шаблон:Chembox Isoquercetin, isoquercitrin or isotrifoliin[1] is a flavonoid, a type of chemical compound. It is the 3-O-glucoside of quercetin. Isoquercitrin can be isolated from various plant species including Mangifera indica (mango)[2] and Rheum nobile (the Noble rhubarb). It is also present in the leaves of Annona squamosa, Camellia sinensis (tea).[3][4] and Vestia foetida[5]

Spectral data

The lambda-max for isoquercetin is 254.8 and 352.6 nm.

Potential clinical uses

Isoquercetin is presently being investigated for prevention of thromboembolism in selected cancer patients[6] and as an anti-fatigue agent in kidney cancer patients treated with sunitinib.[7]

There is a single case report of its use in the successful treatment of prurigo nodularis, a difficult to treat pruritic eruption of the skin.[8]

However it belongs to the PAINS (Pan-assay interference compounds) categories of chemicals.[9]

References

Шаблон:Reflist

See also

Шаблон:Flavonol

  1. Шаблон:Cite web
  2. Шаблон:Cite journal
  3. Шаблон:Cite journal
  4. Шаблон:Cite journal
  5. C. Brevis, M. Quezada, P. Bustamante, L. Carrasco, A. Ruiz, S. Donoso, Huevil (Vestia foetida) poisoning of cattle in Chile The Veterinary record 156(14):452-3 May 2005
  6. NCT02195232
  7. NCT02446795
  8. Шаблон:Cite journal
  9. Шаблон:Cite journal