Английская Википедия:1,2-Dithiolane
1,2-Dithiolane is an organosulfur compound with the formula Шаблон:Chem2. It is also classified as a heterocycle derived from cyclopentane by replacing two methylene bridges (-Шаблон:Chem- units) with a disulfide group. 1,3-Dithiolane is an isomer. The parent molecule is not important but substituted derivatives, especially lipoic acid and its derivatives, are important. Several occur in foods.[1]
1,2-Dithiolane is the disulfide derived from 1,3-propanedithiol. It is however unstable with respect to polymerization.[2]
Substituted derivatives of 1,2-dithiolane are found in some foods, such as asparagusic acid in asparagus.[3] The 4-dimethylamino derivative nereistoxin was the inspiration for insecticides that act by blocking the nicotinic acetylcholine receptor.[4]
Lipoic acid is essential for aerobic metabolism in mammals and also has strong affinity with many metals including gold, molybdenum, and tungsten.[5] Other 1,2-dithiolanes have relevance in nanomaterials such as gold nanoparticles or transition metal dichalcogenide monolayers (TMDs) (MoS2 and WS2).[6][7][8]
-
asparagusic acid
-
nereistoxin, from which insecticides including cartap and bensultap were derived
-
lipoic acid
References
External links
