Английская Википедия:1-aminocyclopropane-1-carboxylate deaminase

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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a 1-aminocyclopropane-1-carboxylate deaminase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

1-aminocyclopropane-1-carboxylate + H2O <math>\rightleftharpoons</math> 2-oxobutanoate + NH3

Thus, the two substrates of this enzyme are 1-aminocyclopropane-1-carboxylate and H2O, whereas its two products are 2-oxobutanoate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing). This enzyme is also called 1-aminocyclopropane-1-carboxylate endolyase (deaminating). This enzyme participates in propanoate metabolism. It employs one cofactor, pyridoxal phosphate.

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, and Шаблон:PDB link.

References

Шаблон:Reflist

Шаблон:Carbon-nitrogen non-peptide hydrolases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:3.5-enzyme-stub