Английская Википедия:2-oxoaldehyde dehydrogenase (NAD+)

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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a 2-oxoaldehyde dehydrogenase (NAD+) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

a 2-oxoaldehyde + NAD+ + H2O <math>\rightleftharpoons</math> a 2-oxo acid + NADH + H+

The 3 substrates of this enzyme are 2-oxoaldehyde, NAD+, and H2O, whereas its 3 products are 2-oxo acid, NADH, and H+.

This enzyme participates in pyruvate metabolism.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-oxoaldehyde:NAD+ 2-oxidoreductase. Other names in common use include:

  • alpha-ketoaldehyde dehydrogenase
  • methylglyoxal dehydrogenase
  • NAD+-linked alpha-ketoaldehyde dehydrogenase
  • 2-ketoaldehyde dehydrogenase
  • NAD+-dependent alpha-ketoaldehyde dehydrogenase
  • 2-oxoaldehyde dehydrogenase (NAD+)

See also

References

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Шаблон:Aldehyde/Oxo oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


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