Английская Википедия:2-oxopropyl-CoM reductase (carboxylating)

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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a 2-oxopropyl-CoM reductase (carboxylating) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

2-mercaptoethanesulfonate + acetoacetate + NADP+ <math>\rightleftharpoons</math> 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH

The 3 substrates of this enzyme are 2-mercaptoethanesulfonate, acetoacetate, and NADP+, whereas its 3 products are 2-(2-oxopropylthio)ethanesulfonate, CO2, and NADPH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-mercaptoethanesulfonate, acetoacetate:NADP+ oxidoreductase (decarboxylating). Other names in common use include NADPH:2-(2-ketopropylthio)ethanesulfonate, oxidoreductase/carboxylase, and NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link and Шаблон:PDB link.

References

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Шаблон:Sulfur oxidoreductases Шаблон:Enzymes Шаблон:Portal bar