Английская Википедия:23S rRNA (adenine2085-N6)-dimethyltransferase

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Шаблон:Short description Шаблон:Infobox enzyme 23S rRNA (adenine2085-N6)-dimethyltransferase (Шаблон:EC number, ErmC' methyltransferase, ermC methylase, ermC 23S rRNA methyltransferase, rRNA:m6A methyltransferase ErmC', ErmC', rRNA methyltransferase ErmC' ) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine2085-N6)-dimethyltransferase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + adenine2085 in 23S rRNA <math>\rightleftharpoons</math> 2 S-adenosyl-L-homocysteine + N6-dimethyladenine2085 in 23S rRNA

ErmC is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalysing the methylation of 23S rRNA at adenine2085.

References

Шаблон:Reflist

External links

Шаблон:One carbon transferases Шаблон:Enzymes Шаблон:Portal bar