Английская Википедия:3-carboxy-cis,cis-muconate cycloisomerase

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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a 3-carboxy-cis,cis-muconate cycloisomerase (Шаблон:EnzExplorer) is an enzyme that catalyzes the chemical reaction

2-carboxy-2,5-dihydro-5-oxofuran-2-acetate <math>\rightleftharpoons</math> cis,cis-butadiene-1,2,4-tricarboxylate

Hence, this enzyme has one substrate, 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate, and one product, cis,cis-butadiene-1,2,4-tricarboxylate.

This enzyme belongs to the family of isomerases, specifically intramolecular lyases. The systematic name of this enzyme class is 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). Other names in common use include beta-carboxymuconate lactonizing enzyme, and 3-carboxymuconolactone hydrolase. This enzyme participates in benzoate degradation via hydroxylation.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Шаблон:PDB link.

References

Шаблон:Reflist

Шаблон:Intramolecular Lyases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:Isomerase-stub