Английская Википедия:4-chlorobenzoate—CoA ligase

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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a 4-chlorobenzoate—CoA ligase (Шаблон:EnzExplorer) is an enzyme that catalyzes the chemical reaction

4-chlorobenzoate + CoA + ATP <math>\rightleftharpoons</math> 4-chlorobenzoyl-CoA + AMP + diphosphate

The 3 substrates of this enzyme are 4-chlorobenzoate, CoA, and ATP, whereas its 3 products are 4-chlorobenzoyl-CoA, AMP, and diphosphate.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is 4-chlorobenzoate:CoA ligase. This enzyme participates in 2,4-dichlorobenzoate degradation. It employs one cofactor, magnesium.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link and Шаблон:PDB link.

References

Шаблон:Reflist

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