Английская Википедия:60S ribosomal protein L14

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Шаблон:Short description Шаблон:Infobox gene 60S ribosomal protein L14 is a protein that in humans is encoded by the RPL14 gene.[1][2]

Function

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[2]

Interactions

RPL14 has been shown to interact with PHLDA1.[3]

References

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External links

Further reading

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Шаблон:GeneticTranslation Шаблон:Ribosome subunits

Шаблон:Gene-3-stub