Английская Википедия:AVN-322

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AVN-322 is a 5-hydroxytryptamine subtype 6 receptor antagonist manufactured by Avineuro Pharmaceuticals Inc. that could potentially be used to combat Alzheimer's disease and schizophrenia.[1][2] AVN-322 also reverses the negative effects of scopolamine and MK-80.[2]

The compound is a sister drug to AVN-101 and AVN-211, two similar compounds under trial for treating Alzheimer's.[2] Phase I trials for the drug were initiated in 2009 by Avineuro, and completed in the spring of 2010.[3][4] The trials showed that AVN-322 was tolerated in a range of doses without any adverse effects, and Avineuro released plans to commence Phase II trials later the same year.[4] The plan for further trials was discontinued in 2013.[5]

References

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  1. Ошибка цитирования Неверный тег <ref>; для сносок Medkoo не указан текст
  2. 2,0 2,1 2,2 Шаблон:Cite journal
  3. Шаблон:Cite web
  4. 4,0 4,1 Шаблон:Cite web
  5. Шаблон:Cite web