Английская Википедия:Acyl-CoA dehydrogenase (NADP+)

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Rendering of Crotonyl CoA Carboxylase/Reductase, an oxidoreductase

Structure of Crotonyl CoA carboxylase/reductase. From Streptomycs collinus.

Шаблон:Infobox enzyme In enzymology, an acyl-CoA dehydrogenase (NADP+) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

acyl-CoA + NADP⁺ <math>\rightleftharpoons</math> 2,3-dehydroacyl-CoA + NADPH + H⁺

Thus, the two substrates of this enzyme are acyl-CoA and NADP⁺, whereas its 3 products are 2,3-dehydroacyl-CoA, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl-CoA:NADP+ 2-oxidoreductase. Other names in common use include 2-enoyl-CoA reductase, dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide, phosphate), enoyl coenzyme A reductase, crotonyl coenzyme A reductase, crotonyl-CoA reductase, and acyl-CoA dehydrogenase (NADP+).

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Шаблон:PDB link.

References

• Шаблон:Cite journal
• Шаблон:Cite journal

Шаблон:1.3-enzyme-stub