Английская Википедия:Adiposogenital dystrophy

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Шаблон:Infobox medical condition (new)

Adiposogenital dystrophy is a condition that may be caused by tertiary hypogonadism originating from decreased levels in GnRH. Low levels of GnRH has been associated with defects of the feeding centers of the hypothalamusШаблон:Citation needed, leading to an increased consumption of food and thus caloric intake.

Presentation

It is characterized by:Шаблон:Citation needed

It is usually associated with tumors of the hypothalamus, causing increased appetite and depressed secretion of gonadotropin. It seems to affect males mostly.Шаблон:Citation neededMany overweight children may appear to have the disorder because of the concurrence of obesity and retarded sexual development; these children have no endocrine disturbances, however, and they mature normally after delayed puberty.Шаблон:Citation needed

Diagnosis

Laboratory analysis of the urine from children with Froehlich syndrome typically reveals low levels of pituitary hormones, and that finding may suggest the presence of a lesion on the pituitary. Additional tests are needed before a definite diagnosis of Froehlich syndrome may be made.[1]

Treatment

Pituitary extracts may be administered to replace the missing hormones (hormonal replacement therapy) in patients with Froehlich syndrome. Tumors of the hypothalamus should be surgically removed if possible. Appetite may be very difficult to manage, although weight control depends on this.Шаблон:Citation needed

References

Шаблон:Reflist

External links

Шаблон:Medical resources Шаблон:Hypothalamic disease