Английская Википедия:Alanine dehydrogenase

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Шаблон:Infobox enzyme Alanine dehydrogenase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

L-alanine + H2O + NAD+ <math>\rightleftharpoons</math> pyruvate + NH3 + NADH + H+

The 2 substrates of this enzyme are L-alanine, water, and nicotinamide adenine dinucleotide+ because water is 55M and does not change, whereas its 4 products are pyruvate, ammonia, NADH, and hydrogen ion.

This enzyme participates in taurine and hypotaurine metabolism and reductive carboxylate cycle (Шаблон:CO2 fixation).

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-alanine:NAD+ oxidoreductase (deaminating). Other names in common use include AlaDH, L-alanine dehydrogenase, NAD+-linked alanine dehydrogenase, alpha-alanine dehydrogenase, NAD+-dependent alanine dehydrogenase, alanine oxidoreductase, and NADH-dependent alanine dehydrogenase. T

Structure

Alanine dehydrogenase contains both a N-terminus[1] and C-terminus domains.[2][3]

References

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Further reading

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Шаблон:CH-NH2 oxidoreductases Шаблон:Enzymes Шаблон:Portal bar