Английская Википедия:Ambroxide

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Ambroxide, widely known by the brand name Ambroxan, is a naturally occurring terpenoid and one of the key constituents responsible for the odor of ambergris. It is an autoxidation product of ambrein.[1] Ambroxide is used in perfumery for creating ambergris notes and as a fixative.[1] Small amounts (< 0.01 ppm) are used as a flavoring in food.[2]

Synthesis

Ambroxide is synthesized from sclareol, a component of the essential oil of clary sage.[3] Sclareol is oxidatively degraded to a lactone, which is hydrogenated to the corresponding diol.[4] The resulting compound is dehydrated to form ambroxide.[1]

Файл:Ambroxide synthesis sclareol.svg
Conversion of sclareol to ambroxide
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References

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