Английская Википедия:Amino-acid racemase

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Шаблон:Infobox enzyme In enzymology, an amino-acid racemase (Шаблон:EnzExplorer) is an enzyme that catalyzes the chemical reaction

an L-amino acid <math>\rightleftharpoons</math> a D-amino acid

Hence, this enzyme has one substrate, L-amino acid, and one product, D-amino acid.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is amino-acid racemase. This enzyme is also called L-amino acid racemase. This enzyme participates in 4 metabolic pathways: glycine, serine and threonine metabolism, cysteine metabolism, D-glutamine and D-glutamate metabolism, and D-arginine and D-ornithine metabolism. It employs one cofactor, pyridoxal phosphate.

Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, and Шаблон:PDB link.

References

Шаблон:Reflist

Шаблон:Racemases and epimerases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:Isomerase-stub