Английская Википедия:Amlodipine/benazepril

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Amlodipine/benazepril, sold under the brand name Lotrel among others, is a fixed-dose combination medication used to treat high blood pressure.[1] It is a combination of amlodipine, as the besilate, a calcium channel blocker, and benazepril, an angiotensin converting enzyme inhibitor.[1] It may be used if a single agent is not sufficient.[1] It is taken by mouth.[1]

Common side effects include cough, dizziness, and swelling.[1] Serious side effects may include angioedema, myocardial infarction, high blood potassium, liver problems, and low blood pressure.[1] Use in pregnancy is not recommended.[1] Amlodipine works by increasing the size of arteries while benazepril works by decreasing renin-angiotensin-aldosterone system activity.[1]

The combination was approved for medical use in the United States in 1995.[2] It is available as a generic medication.[3] In 2020, it was the 169th most commonly prescribed medication in the United States, with more than 3Шаблон:Nbspmillion prescriptions.[4][5]

Medical uses

It is used to treat high blood pressure.[1] It is not a first-line treatment.[6]

References

Шаблон:Reflist

External links

Шаблон:Calcium channel blockers Шаблон:ACE inhibitors Шаблон:Portal bar

Шаблон:Cardiovascular-drug-stub

  1. 1,0 1,1 1,2 1,3 1,4 1,5 1,6 1,7 1,8 Ошибка цитирования Неверный тег <ref>; для сносок Lotrel FDA label не указан текст
  2. Шаблон:Cite web
  3. Шаблон:Cite book
  4. Шаблон:Cite web
  5. Шаблон:Cite web
  6. Шаблон:Cite journal