Английская Википедия:Arachidonic acid 5-hydroperoxide

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Шаблон:Chembox Arachidonic acid 5-hydroperoxide (5-hydroperoxyeicosatetraenoic acid, 5-HPETE) is an intermediate in the metabolism of arachidonic acid by the ALOX5 enzyme in humans or Alox5 enzyme in other mammals. The intermediate is then further metabolized to: a) leukotriene A4 which is then metabolized to the chemotactic factor for leukocytes, leukotriene B4, or to contractors of lung airways, leukotriene C4, leukotriene D4, and leukotriene E4; b) the leukocyte chemotactic factors, 5-Hydroxyicosatetraenoic acid and 5-oxo-eicosatetraenoic acid; or c) the specialized pro-resolving mediators of inflammation, lipoxin A4 and lipoxin B4.[1][2]

Файл:Eicosanoid synthesis.svg
Eicosanoid synthesis.

Шаблон:Eicosanoids Шаблон:Leukotrienergics

References

Шаблон:Reflist


Шаблон:Alkene-stub Шаблон:Biochem-stub