Английская Википедия:Befuraline

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Шаблон:Short description Шаблон:Cs1 config Шаблон:Drugbox

Befuraline (DIV-154) is a psychoactive drug and member of the piperazine chemical class which was developed in Germany in the 1970s.[1] Befuraline has stimulant and antidepressant effects and has seen some use in Germany and France, although it has never become widely used.[2] Befuraline's active metabolite benzylpiperazine is likely to contribute to its effects.

Synthesis

Файл:Befuraline synthesis.svg
Synthesis:[1] Patent:[3]

A one-step coupling between coumarilic acid (benzofuran-2-carboxylic acid) [496-41-3] (1) and benzylpiperazine (BzP) (2) gives an amide, and hence Befuraline (3).

See also

References

Шаблон:Reflist

Шаблон:Antidepressants Шаблон:Stimulants Шаблон:Piperazines


Шаблон:Psychoactive-stub

  1. 1,0 1,1 Шаблон:Cite journal
  2. Шаблон:Cite journal
  3. DE2157424 idem Rolf-Ortwin Weber, Alfons Soder, Istvan Boksay, Шаблон:US patent (1980 to Hoechst Aktiengesellschaft).