Английская Википедия:Betaine-aldehyde dehydrogenase

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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a betaine-aldehyde dehydrogenase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

betaine aldehyde + NAD+ + H2O <math>\rightleftharpoons</math> betaine + NADH + 2 H+

The 3 substrates of this enzyme are betaine aldehyde, NAD+, and H2O, whereas its 3 products are betaine, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is betaine-aldehyde:NAD+ oxidoreductase. Other names in common use include betaine aldehyde oxidase, BADH, betaine aldehyde dehydrogenase, and BetB. This enzyme participates in glycine, serine and threonine metabolism.

Structural studies

Шаблон:As of, 4 structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, and Шаблон:PDB link.

References

Шаблон:Reflist

Шаблон:Aldehyde/Oxo oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:1.2-enzyme-stub