Английская Википедия:Bupropion/zonisamide

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Шаблон:Short description Шаблон:Drugbox

Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity.[1][2][3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker, and weak carbonic anhydrase inhibitor.[1] The combination was being developed by Orexigen Therapeutics and reached phase II clinical trials prior to discontinuation.[1][4][5]

See also

References

Шаблон:Reflist

Шаблон:Ion channel modulators Шаблон:Monoamine reuptake inhibitors Шаблон:Nicotinic acetylcholine receptor modulators


Шаблон:Nervous-system-drug-stub