Английская Википедия:CEP63

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Шаблон:Short description Шаблон:Infobox gene Centrosomal protein of 63 kDa is a protein that in humans is encoded by the CEP63 gene.[1][2] Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Function

This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.[2] Recent computational analysis revealed pathogenic property of L61P point mutation in CEP63 protein that affected its native structural conformation.[3]

Interactions

CEP63 has been shown to interact with DISC1,[4] CEP152 and CDK1.[3]

References

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External links

Further reading

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Шаблон:Centrosome


Шаблон:Gene-3-stub