Английская Википедия:Calpain-1 catalytic subunit

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Шаблон:Short description Шаблон:Infobox gene Calpain-1 catalytic subunit (CANP 1) is a protein that in humans is encoded by the CAPN1 gene.[1][2][3]

Function

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1.[3]

Interactions

CAPN1 has been shown to interact with PSEN2.[4]

References

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Further reading

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External links

Шаблон:PDB Gallery Шаблон:Cysteine proteases


Шаблон:Gene-11-stub