Английская Википедия:Carr index

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Шаблон:Short description The Carr index (Carr's index or Carr's Compressibility Index) is an indicator of the compressibility of a powder. It is named after the scientist Ralph J. Carr, Jr.

The Carr index is calculated by the formula <math>C=100\frac{\rho_T-\rho_B}{\rho_T}</math>, where <math>\rho_B</math> is the freely settled bulk density of the powder, and <math>\rho_T</math> is the tapped bulk density of the powder after "tapping down". It can also be expressed as <math>C=100(1-\rho_B/\rho_T)</math>.

The Carr index is frequently used in pharmaceutics as an indication of the compressibility of a powder. In a free-flowing powder, the bulk density and tapped density would be close in value, therefore, the Carr index would be small. On the other hand, in a poor-flowing powder where there are greater interparticle interactions, the difference between the bulk and tapped density observed would be greater, therefore, the Carr index would be larger. A Carr index greater than 25 is considered to be an indication of poor flowability, and below 15, of good flowability.

Another way to measure the flow of a powder is the Hausner ratio, which can be expressed as <math>H=\rho_T/\rho_B</math>.

Both the Hausner ratio and the Carr index are sometimes criticized, despite their relationships to flowability being established empirically, as not having a strong theoretical basis. Use of these measures persists, however, because the equipment required to perform the analysis is relatively cheap and the technique is easy to learn.

General Bibliography

Шаблон:Pharmacology-stub