Английская Википедия:Ceftezole

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Шаблон:Short description Шаблон:Drugbox

Ceftezole (or ceftezol) is a semisynthetic first-generation cephalosporin antibiotic.[1]

Ceftezole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.Шаблон:Cn

Ceftezole is having (1,3,4-thiadiazol-2-ylsulfanyl)methyl and [2-(1H-tetrazol-1-yl)acetamido side groups located at positions 3 and 7 respectively. It is a cephalosporin and a member of thiadiazoles.Шаблон:Cn

References

Шаблон:Reflist

Note

External links

Шаблон:CephalosporinAntiBiotics


Шаблон:Antibiotic-stub