Английская Википедия:Cholesterol sulfate

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Cholesterol sulfate, or cholest-5-en-3β-ol sulfate, is an endogenous steroid and the C3β sulfate ester of cholesterol.[1][2] It is formed from cholesterol by steroid sulfotransferases (SSTs) such as SULT2B1b (also known as cholesterol sulfotransferase)[2] and is converted back into cholesterol by steroid sulfatase (STS).[1] Accumulation of cholesterol sulfate in the skin is implicated in the pathophysiology of X-linked ichthyosis, a congenital disorder in which STS is non-functional and the body cannot convert cholesterol sulfate back into cholesterol.[1][2]

See also

References

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Шаблон:Endogenous steroids Шаблон:Cholesterol and steroid intermediates


Шаблон:Steroid-stub