Файл:Scanning electron microscopy (SEM) images of C lusitaniae on filament-inducing media journal pone 0044192.pngScanning electron microscopy (SEM) images of C. lusitaniae on filament-inducing media. Cells grown on V8 (pH = 7) media for 7 days at 37°C were processed for SEM, and imaged (see Materials and Methods). Scale bars for upper panel (1000x) and lower panel (5000x) images represent 10 µm and 2 µm, respectively. WT (ATCC42720), cnb1 mutant (YC198), and crz1 mutant (YC187)
Clavispora lusitaniae, formerly also known by the anamorph name Candida lusitaniae, is a species of yeast in the genus Candida or Clavispora. The species name is a teleomorph name.[1]
Clavispora lusitaniae was first identified as a human pathogen in 1979.[2]
Clavispora lusitaniae was initially described as a rare cause of fungemia, with fewer than 30 cases reported between 1979 and 1990. However, there has been a marked increase in the number of recognized cases of candidemia due to this organism in the last two decades.Шаблон:Reltime Bone marrow transplantation and high-dose cytoreductive chemotherapy have both been identified as risk factors for infections with this organism.[3]
These patients are often neutropenic for extended periods of time, leaving them susceptible to bacterial and fungal infections, including Candidal infections. Some investigators have theorized that the widespread use of Amphotericin B empiric antifungal therapy selects for infections with Candida lusitaniae.[4]
The U.S. CDC has cautioned that the use of the teleomorph name Clavispora lusitaniae for the species can be misleading, because it does not "include the word Candida even though this organism is indeed a species of Candida".[1]
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