Английская Википедия:Collagen, type I, alpha 2

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Шаблон:Short description Шаблон:Cs1 config Шаблон:Infobox gene Collagen alpha-2(I) chain is a protein that in humans is encoded by the COL1A2 gene.[1][2]

This gene encodes one of the chains for type I collagen, the fibrillar collagen found in most connective tissues. Mutations in this gene are associated with osteogenesis imperfecta, Cardiac-valvular, and Arthrochlasia type Ehlers-Danlos syndrome, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for alpha-1 type I collagen, since alpha-2 is less abundant. Multiple messages for this gene result from multiple polyadenylation signals, a feature shared by most of the other collagen genes.[3]

See also

References

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Further reading

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External links

Шаблон:Fibrous proteins

Шаблон:Gene-7-stub