Английская Википедия:Conopharyngine

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Conopharyngine is the major alkaloid present in the leaves and stem-bark of Tabernaemontana pachysiphon and Conopharyngia durissima.[1][2][3] It is closely related voacangine and coronaridine. Conopharyngine pseudoindoxyl, a derivative of it, is also found in the same plant Tabernaemontana pachysiphon.[4]

Pharmacology

It possess central nervous system stimulant activity and produces bradycardia and hypotension in cats. It has weak acetylcholinesterase inhibitory activity and significantly increases hexobarbitone induced sleeping time.[5]

Toxicity

It has low intravenous toxicity in mice (LD50 = 143 mg/kg).[5]

See also

References

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Шаблон:Alkaloid-stub