Английская Википедия:Cyanoacetamide

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2-Cyanoacetamide is an organic compound. It is an acetic amide with a nitrile functional group.

Uses

Cyanoacetamide is used in spectrofluorimetric methods to determine the activity of antihistamine H1 receptor antagonistic drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride.[1]

Preparation

2-Cyanoacetamide is prepared from chloroacetic acid via Kolbe nitrile synthesis[2] followed by Fischer esterification and ester aminolysis.[3]

See also

References

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