Английская Википедия:Cynthia Reinhart-King

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Cynthia "Cindy" Reinhart-King is an American biomedical engineer who is a University Distinguished Professor at Vanderbilt University. Her research considers cell motility and adhesion. She serves as president of the Biomedical Engineering Society.

Early life and education

Reinhart-King studied chemical engineering and biology at Massachusetts Institute of Technology.[1] She studied integrin-mediated signalling alongside Doug Lauffenburger.[1] Integrin-mediated signalling describes the molecular signals that are initiated when an extracellular ligand binds to an integrin on the cellular surface, resulting in the regulation of a downstream cellular process. After graduating, she joined the University of Pennsylvania as a doctoral student, where she worked on cell adhesion in the endothelium.[2] She moved to the University of Rochester for postdoctoral research, studying atherosclerosis with Bradford Berk.[1]

Research and career

Reinhart-King's research has helped understanding of cancer progression.[3] She has monitored disease progression at the molecular, cellular and tissue level.[4] Her analytical strategy combines cellular imaging with mechanical measurements, histology and biochemical assays.[5] She showed how the cellular matrix stiffens after tumour formation, promoting tumour growth and impacting the effectiveness of cancer treatments.[3] Her lab have demonstrated that although cancer cells move quickly during metastasis, their migration through the body occurs via the most easy pathways.[6] In particular, they favor wider spaces that are easier navigated than smaller and more confined ones.[7]

Reinhart-King has also investigated diabetic retinopathy. This condition can cause blindness in diabetic patients.[4] She started her independent scientific career at Cornell University.[8]

In 2021, Reinhart-King became President Elect of the Biomedical Engineering Society.[9] She was made Senior Associate Dean for Research at Vanderbilt University in 2022.[10] She has been involved with science policy, serving as an expert advisor to the federal government of the United States on biotechnology and biomanufacturing.[11]

Awards and honors

Selected publications

Personal life

Reinhart-King is married to Michael King, the J. Lawrence Wilson Professor of Engineering at Vanderbilt University.[21][22] Together they have two children.[1]

References

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