Английская Википедия:Cysteine lyase

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Шаблон:Infobox enzyme The enzyme cysteine lyase (EC 4.4.1.10) [1] catalyzes the chemical reaction

L-cysteine + sulfite <math>\rightleftharpoons</math> L-cysteate + hydrogen sulfide

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming). Other names in common use include cysteine (sulfite) lyase, and L-cysteine hydrogen-sulfide-lyase (adding sulfite). This enzyme participates in cysteine and taurine metabolism. It employs one cofactor, pyridoxal phosphate.

Evolution

Genes encoding cysteine lyase (CL) originated around 300 million years ago by a tandem gene duplication and neofunctionalization of cystathionine β-lyase (CBS) shortly after the split of mammalian and reptilian lineages. CL genes are found only in Sauropsida where they are involved in a metabolic pathway for sulfur metabolism in the chicken egg.[2]

References

Шаблон:Reflist

Шаблон:Carbon-sulfur lyases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:Lyase-stub