Английская Википедия:Diaminopimelate dehydrogenase

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Шаблон:Infobox enzyme In enzymology, a diaminopimelate dehydrogenase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

meso-2,6-diaminoheptanedioate + H2O + NADP+ <math>\rightleftharpoons</math> L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+

The 3 substrates of this enzyme are meso-2,6-diaminoheptanedioate, H2O, and NADP+, whereas its 4 products are L-2-amino-6-oxoheptanedioate, NH3, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating). Other names in common use include meso-alpha,epsilon-diaminopimelate dehydrogenase, and meso-diaminopimelate dehydrogenase. This enzyme participates in lysine biosynthesis.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, and Шаблон:PDB link.

References

Шаблон:Reflist

Шаблон:CH-NH2 oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:1.4-enzyme-stub