Английская Википедия:Diclofenac/misoprostol

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Diclofenac/misoprostol, sold under the brand name Arthrotec, is a fixed-dose combination medication that contains:

In the United Kingdom it is marketed by Pharmacia and it is indicated for prophylaxis against NSAID-induced gastroduodenal ulceration in people requiring diclofenac for rheumatoid arthritis or osteoarthritis.[1]

The American College of Rheumatology and a Canadian consensus report both recommend GI-protective agents such as misoprostol be combined with long term NSAID therapy and a review concluded that diclofenac/misoprostol is a cost effective treatment in patients requiring long term NSAID therapy who are at increased risk of developing gastropathy.[2]

Contraindications

Arthrotec must not be taken during pregnancy, as it may deform or otherwise harm the fetus, or lead to miscarriage. This may be accompanied by potentially dangerous bleeding, possibly requiring surgery and potentially leading to infertility or death.[1]

References

Шаблон:Reflist

External links

Шаблон:NSAIDs Шаблон:Portal bar


Шаблон:Musculoskeletal-drug-stub Шаблон:Analgesic-stub

  1. 1,0 1,1 Ошибка цитирования Неверный тег <ref>; для сносок ="Arthrotec не указан текст
  2. Шаблон:Cite journal